abstract：:Human social interactions often involve carefully synchronized behaviours. Musical performance in particular features precise timing and depends on the differentiation and coordination of musical/social roles. Here, we study the influence of musical/social roles, individual musicians and different ensembles on rhythmi...

authors： Jacoby N,Polak R,London J

更新日期：2021-10-11 00:00:00

abstract：:Humans perceive and spontaneously move to one or several levels of periodic pulses (a meter, for short) when listening to musical rhythm, even when the sensory input does not provide prominent periodic cues to their temporal location. Here, we review a multi-levelled framework to understanding how external rhythmic in...

authors： Lenc T,Merchant H,Keller PE,Honing H,Varlet M,Nozaradan S

更新日期：2021-10-11 00:00:00

abstract：:As an alternative to perfluorooctane sulfonate (PFOS), 6:2 chlorinated polyfluorinated ether sulfonate (F53B) has emerged in the Chinese market in recent years and has been frequently detected in the aquatic environment, but its ecological risk assessment is limited. In this study, zebrafish embryos and larvae were se...

authors： Liu S,Lai H,Wang Q,Martínez R,Zhang M,Liu Y,Huang J,Deng M,Tu W

更新日期：2021-10-10 00:00:00

abstract：:Fluoroquinolones (FQs) have raised significant concerns due to their ubiquitous occurrence and promoting of antimicrobial resistance (AMR). In this study, a molecularly imprinted polymer-diffusive gradient in thin-films (MIP-DGT) sampler is developed for selective measurement of FQs in waters by using a commercial ava...

authors： Liu SS,Li JL,Ge LK,Li CL,Zhao JL,Zhang QQ,Ying GG,Chen CE

更新日期：2021-10-10 00:00:00

abstract：:The outbreak and rapid spread of coronavirus disease 2019 (COVID-19) has had a huge impact on the lives and safety of people around the world. Chest CT is considered an effective tool for the diagnosis and follow-up of COVID-19. For faster examination, automatic COVID-19 diagnostic techniques using deep learning on CT...

authors： Hu K,Huang Y,Huang W,Tan H,Chen Z,Zhong Z,Li X,Zhang Y,Gao X

更新日期：2021-10-07 00:00:00

abstract：:The vibrational study of the pyraclostrobin (methyl N-(2-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxymethyl}phenyl) N-methoxycarbamate) molecule, a synthetic fungicide for agricultural uses, was performed. Pyraclostrobin belongs to the strobilurin family and acts by inhibiting the fungus respiratory chain at the level of ...

authors： Dominguez AN,Emmert GE,Gil DM,Álvarez RMS

更新日期：2021-10-05 00:00:00

abstract：:Inhibition of FGF/FGFR signaling is a promising strategy for the treatment of malignances dependent from FGF stimulation, including multiple myeloma (MM). The steroidal derivative NSC12 (compound 1) is a pan-FGF trap endowed with antitumor activity in vivo. Chemical modifications of compound 1 were explored to investi...

authors： Castelli R,Taranto S,Furiassi L,Bozza N,Marseglia G,Ferlenghi F,Rivara S,Retini M,Bedini A,Spadoni G,Matarazzo S,Ronca R,Presta M,Mor M,Giacomini A

更新日期：2021-10-05 00:00:00

abstract：:Despite significant improvements of new treatment options, cancer continues to represent as one of the most common and fatal disease. The EGFR signaling pathway is considered as a significant approach in targeted therapy of cancers. Blocking the EGFR-driven pathway by inhibiting the intracellular tyrosine kinase domai...

authors： Ayati A,Moghimi S,Toolabi M,Foroumadi A

更新日期：2021-10-05 00:00:00

abstract：:Curcumin, described as a wonder drug owing to various medicinal, viz. anticancer, antiviral, anti-inflammatory etc., properties, can also be seen as a model molecular system to study strong intra-molecular OH----O hydrogen bonds which govern its physico-chemical properties. The study of these hydrogen bonds is importa...

authors： Bhatt H,Thomas S,Vishwakarma SR

更新日期：2021-10-05 00:00:00

abstract：:The sensitive detection and identification of toxicants in oily matrices have suffered from difficulty in poisoning incidents, therefore it is necessary to develop the rapid and efficient analytical method to realize the on-site screening and analyzing. In this report, the surface-enhanced Raman spectroscopy (SERS) me...

authors： Wang Y,Li P,Lin D,Chen J,Zhang Y,Yang L

更新日期：2021-10-05 00:00:00

abstract：:Currently, smallpox, caused by the variola virus belonging to the poxvirus family, has been completely eradicated according to the WHO. However, other representatives of poxviruses, such as vaccinia virus, cowpox virus, ectromelia virus, monkeypox virus, mousepox virus and others, remain in the natural environment and...

authors： Shiryaev VA,Skomorohov MY,Leonova MV,Bormotov NI,Serova OA,Shishkina LN,Agafonov AP,Maksyutov RA,Klimochkin YN

更新日期：2021-10-05 00:00:00

abstract：:In the search for new anti-influenza virus (IV) compounds, we have identified the 1,2,4-triazolo[1,5-a]pyrimidine (TZP) as a very suitable scaffold to obtain compounds able to disrupt IV RNA-dependent RNA polymerase (RdRP) PA-PB1 subunits heterodimerization. In this work, in order to acquire further SAR insights for t...

authors： Pismataro MC,Felicetti T,Bertagnin C,Nizi MG,Bonomini A,Barreca ML,Cecchetti V,Jochmans D,De Jonghe S,Neyts J,Loregian A,Tabarrini O,Massari S

更新日期：2021-10-05 00:00:00

abstract：:The ability to discriminate between different ionic species, termed ion selectivity, is a key feature of ion channels and forms the basis for their physiological function. Members of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily of trimeric ion channels are typically sodium selective, but to a surpris...

authors： Sheikh ZP,Wulf M,Friis S,Althaus M,Lynagh T,Pless SA

更新日期：2021-10-04 00:00:00

abstract：:A digital twin (DT) is classically defined as the virtual replica of a real-world product, system, being, communities, even cities that are continuously updated with data from its physical counterpart, as well as its environment. It bridges the virtual cyberspace with the physical entities and, as such, is considered ...

authors： Jiang Y,Yin S,Li K,Luo H,Kaynak O

更新日期：2021-10-04 00:00:00

abstract：:Mitochondrial DNA (mtDNA) has been suggested to drive immune system activation, but the induction of interferon signaling by mtDNA has not been demonstrated in a Mendelian mitochondrial disease. We initially ascertained two patients, one with a purely neurological phenotype and one with features suggestive of systemic...

authors： Lepelley A,Della Mina E,Van Nieuwenhove E,Waumans L,Fraitag S,Rice GI,Dhir A,Frémond ML,Rodero MP,Seabra L,Carter E,Bodemer C,Buhas D,Callewaert B,de Lonlay P,De Somer L,Dyment DA,Faes F,Grove L,Holden S,Hully M,

更新日期：2021-10-04 00:00:00

abstract：:Over the past few decades, increasing efforts have been made to improve the understanding of, and treatment options for, lung adenocarcinoma (LUAD). However, considering the heterogeneity of LUAD, precise proteomics-based characterization at the molecular level is an urgent clinical requirement for effective treatment...

authors： Xie Q,Wang D,Luo X,Li Z,Hu A,Yang H,Tang J,Gao P,Sun T,Kong L

更新日期：2021-10-01 00:00:00

abstract：:Aberrant C-C motif chemokine ligand 5 (CCL5) is associated with disease progression, poor prognosis and chemotherapy resistance in human malignancy. The tumor microenvironment (TME) contributes to chemotherapy resistance. However, the role of cancer-associated fibroblasts (CAFs)-derived CCL5 is not well documented. He...

authors： Sun X,Chen Z

更新日期：2021-10-01 00:00:00

abstract：:States of oral health and disease reflect the compositional and functional capacities of, as well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a highly dynamic microbial environment that harbors many distinct substrata and microenvironments that house diverse microbial commun...

authors： Sedghi L,DiMassa V,Harrington A,Lynch SV,Kapila YL

更新日期：2021-10-01 00:00:00

abstract：:Owing to the presence of known tumor-specific viral antigens, human papillomavirus (HPV)-associated cancers are well suited for treatment with immunotherapy designed to unleash, amplify or replace the T cell arm of the adaptive immune system. Immune checkpoint blockade designed to unleash existing T cell immunity is c...

authors： Lee MY,Allen CT

更新日期：2021-10-01 00:00:00

abstract：:Anthelmintics, drugs against parasitic worms, are frequently used in livestock and might act as danger environmental microcontaminants. The present study was designed to monitor the possible circulation of common anthelmintic drug albendazole (ABZ) and its metabolites in the real agriculture conditions. The sheep were...

authors： Navrátilová M,Raisová Stuchlíková L,Matoušková P,Ambrož M,Lamka J,Vokřál I,Szotáková B,Skálová L

更新日期：2021-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Stillbirth has a high global prevalence and has not improved despite other advances in maternal and perinatal outcomes in the last 20 years. The global applicability of research is challenged by the fact that most evidence originates from high-income countries, whereas the burden is greatest in low- a...

authors： Ishak M,Khalil A

更新日期：2021-10-01 00:00:00

abstract：:Loss of cognitive function in the aging population, particular those with Alzheimer disease, presents unique challenges to health practitioners. For the dental practitioner these include management of periodontal diseases, caries, and other dental conditions in this special population. It is well established in the co...

authors： Ryder MI,Xenoudi P

更新日期：2021-10-01 00:00:00

abstract：:Deca-brominated diphenyl ether (BDE-209) is shown to be persistent in soil and it's urgent to find an effective method to remove BDE-209 from contaminated soil. In this study, the investigation of BDE-209 degradation in three different rice-vegetable rotation soils induced by electron beam (E-beam) irradiation under f...

authors： Zhao P,Ye Q,Zheng Y,Whalen JK,Zhang S,Wang W

更新日期：2021-10-01 00:00:00

abstract：:Threatened or endangered reptiles, such as sea turtles, are generally understudied within the field of wildlife toxicology, with even fewer studies on how contaminants affect threatened species reproduction. This paper aimed to better inform threatened species conservation by systematically and quantitatively reviewin...

authors： Barraza AD,Finlayson KA,Leusch FDL,van de Merwe JP

更新日期：2021-10-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is one of the most devastating cancer types, accounting for >80% of lung cancer cases. The median relative survival time of patients with NSCLC is <1 year. Lysine acetylation is a major post-translational modification that is required for various biological processes, and abnormal pr...

authors： Zheng M,Hu C,Wu M,Chin YE

更新日期：2021-10-01 00:00:00

abstract：:The deregulation of histone deacetylase 1 (HDAC1) is reportedly involved in the progression of several cancer types. However, its function in endometrial cancer remains unknown. The aim of the present study was to clarify the role of HDAC1 in aerobic glycolysis and the progression of endometrial cancer. Lentiviral vec...

authors： Wu Q,Zhang W,Liu Y,Huang Y,Wu H,Ma C

更新日期：2021-10-01 00:00:00

abstract：:Hemorrhoids and fistula are considered the most common anorectal conditions in the general population. These conditions affect the quality of a patient's life by causing pain and bleeding during defecation or even in the resting state. Lower grades of hemorrhoids may be controlled by traditional measures. However, sur...

authors： Porwal A,Kundu GC,Bhagwat G,Butti R

更新日期：2021-10-01 00:00:00

abstract：:Myocardial injury is the primary manifestation of multiple organ dysfunction during sepsis, however, the mechanisms underlying sepsis‑induced myocardial injury remain unclear. Similarly, no effective therapeutics have yet been developed for myocardial injury. In the present study, the role of the NOD‑like receptor 3 (...

authors： Qiu J,Xiao X,Gao X,Zhang Y

更新日期：2021-10-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the main causes of mortality. Recent studies suggest that cancer stem cells (CSCs) can survive after chemotherapy and promote tumor invasiveness and aggression. According to a higher hierarchy complexity of CSC, different protocols for isolation, expansion, and characterization have b...

authors： Garza-Treviño EN,Martínez-Rodríguez HG,Delgado-González P,Solís-Coronado O,Ortíz-Lopez R,Soto-Domínguez A,Treviño VM,Padilla-Rivas GR,Islas-Cisneros JF,Quiroz-Reyes AG,Said-Fernández SL

更新日期：2021-10-01 00:00:00

abstract：:Alloplastic replacement of temporomandibular joint is the preferred treatment for temporomandibular joint ankylosis (TMJA) in ankylosing spondylitis (AS) patients. These patients exhibit neck rigidity due to fixed flexion deformity or fusion of vertebrae that make the intubation and surgical positioning of patients di...

authors： Goswami D,Singh A,Yadav P,Roychoudhury A

更新日期：2021-10-01 00:00:00

abstract：:Using a unique cross-national dataset, we explore the interplay between household income, coronavirus-induced anxiety, national context, and self-rated health (SRH) across dozens of countries among more than 13,500 older adults. Based on multilevel models, we find that the emotional anxiety due to COVID-19 negatively ...

authors： Kim HH,Katelyn Kim HJ

更新日期：2021-10-01 00:00:00

abstract：...

authors： Akazawa K,Kagara N,Sota Y,Motooka D,Nakamura S,Miyake T,Tanei T,Naoi Y,Shimoda M,Kim SJ,Noguchi S,Shimazu K

更新日期：2021-10-01 00:00:00

abstract：:Ferroptosis is a non‑apoptotic form of cell death that relies on iron and lipid peroxidation, which is associated with multiple pathological processes in several diseases. Erastin is a small molecule capable of initiating ferroptotic cell death in cancer cells, which has shown great potential for cancer therapy. Howev...

authors： Zhao J,Xu B,Xiong Q,Feng Y,Du H

更新日期：2021-10-01 00:00:00

abstract：:[This corrects the article DOI: 10.1016/j.jcot.2020.06.023.][This corrects the article DOI: 10.1016/j.jcot.2020.04.024.][This corrects the article DOI: 10.1016/j.jcot.2020.10.020.][This corrects the article DOI: 10.1016/j.jcot.2020.09.002.][This corrects the article DOI: 10.1016/j.jcot.2020.07.013.][This corrects the ...

authors：

更新日期：2021-10-01 00:00:00

abstract：:Near-infrared (NIR) emitting probes with very large Stokes' shifts play a crucial role in bioimaging applications, as the optical signals in this region exhibit high signal to background ratio and allow deeper tissue penetration. Herein we illustrate NIR-emitting probe 2 with very large Stokes' shifts (Δλ ≈ 260 - 272 ...

authors： Dahal D,Ojha KR,Pokhrel S,Paruchuri S,Konopka M,Liu Q,Pang Y

更新日期：2021-10-01 00:00:00

abstract：:Pycnodysostosis is a rare autosomal recessive condition caused by the mutation of CTSK gene. CTSK regulates the activity of Cathepsin K which is responsible for osteoclast-mediated bone resorption. This mutation causes the bones to become dense, sclerotic, brittle, and thus, prone to fracture. Affected individuals hav...

authors： Sharma A,Upmanyu A,Parate AR,Kasat VO

更新日期：2021-10-01 00:00:00

abstract：:N‑methyl D‑aspartate receptors (NMDARs) are closely associated with the development, growth and metastasis of cancer. Glutamate receptor, ionotropic, N‑methyl D‑aspartate‑associated protein 1 (GRINA) is a member of the of the NMDAR family, and its aberrant expression is associated with gastric cancer. However, the rol...

authors： Yan Z,Li P,Xue Y,Tian H,Zhou T,Zhang G

更新日期：2021-10-01 00:00:00

abstract：:Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the Transwell cell migration data shown in Fig. 4 were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the ...

authors： Luo J,Li H,Zhang C

更新日期：2021-10-01 00:00:00

abstract：:Hydrological data and total phosphorus (TP) concentration at reservoirs' outlet were combined in a transient complete-mix model to obtain mean input loads and inlet concentration-flow relationships. This approach was designed to investigate the issue of phosphorus pollution in semiarid regions with intermittent rivers...

authors： Rocha MJD,Lima Neto IE

更新日期：2021-10-01 00:00:00

abstract：:Bioplastics are becoming more and more widespread as substitutes for petroleum-derived plastics due to their biodegradability. Bioplastics degradation under different environments has been described and reported to depend mainly on bioplastics' compositions and the environmental conditions. Incomplete degradation duri...

authors： Cucina M,de Nisi P,Tambone F,Adani F

更新日期：2021-10-01 00:00:00